Motor neuron disease‐like phenotype associated with anti‐IgLON5 disease
نویسندگان
چکیده
منابع مشابه
Motor Neuron Disease Associated with Voltage-Gated Potassium Channel Antibodies
Introduction: Antibodies to voltage-gated potassium channels have been implicated in causing a host of peripheral and central nervous system disorders. However, the presence of these antibodies has not been previously associated with motor neuropathy. We describe the first case of acquired motor neuron disease associated with voltage-gated potassium channel antibodies. Case Report: The patient ...
متن کاملMotor Neuron Disease
Neurologists in the 19th century recognized that muscle weakness could be due to primary disorders of muscle or secondary to loss of neuromuscular integrity, as happens when peripheral nerves are cut or when motor neurons degenerate. Furthermore, it was observed that there are forms of motor neuron degeneration which selectively affect upper motor neurons or lower motor neurons. A combination o...
متن کاملAssessing motor neuron disease.
Hadjikoutis and Wiles draw attention to a number of circumstances in which the serum chloride and bicarbonate can be misleading. They do not mention that they will also be misleading if they are measured when hypercapnia is increasing or decreasing. An exacerbation of hypercapnia will take 4 – 6 days to raise the serum bicarbonate and lower the serum chloride to new steady levels. 1 How long it...
متن کاملMotor neuron disease
Motor neuron disease (MND) represents one ofthe major unsolved problems in neurology. The literature is characterized by numerous speculative theories, mostly derived by analogy with other recognized causes of motor neuron death such as poliomyelitis, or from toxic exposures such as lead poisoning. However, analogous reasoning of this type has not, so far, given insights into MND itself, or res...
متن کاملClinically undetected motor neuron disease in pathologically proven frontotemporal lobar degeneration with motor neuron disease.
BACKGROUND Frontotemporal lobar degeneration with motor neuron disease (FTLD-MND) is a pathological entity characterized by motor neuron degeneration and frontotemporal lobar degeneration. The ability to detect the clinical signs of dementia and motor neuron disease in pathologically confirmed FTLD-MND has not been assessed. OBJECTIVES To determine if all cases of pathologically confirmed FTL...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2018
ISSN: 1755-5930,1755-5949
DOI: 10.1111/cns.13038